Schulz Lab

The Schulz Lab (Kalynn Schulz, PI) is interested in how environmental events shape the developing nervous system and adult behavior. In particular, we use rodent models to investigate the mechanisms by which developmental stress exposure and deviations in pubertal timing confer risk for mental illness.

Schulz K.M., and Sisk, C.L. (2016). The organizing actions of adolescent gonadal steroid hormones on brain and behavioral development. Neuroscience and Biobehavioral Reviews (70) 148-158.

Schulz, K. M., & Sisk, C. L. (In Press). Gonadal hormonal influences on the adolescent brain and trajectories of behavioral development. In  Hormones Brain and Behavior. San Diego CA: Academic Press.

Schulz, K.M., Pearson, J.N., Gasparrini, M.E., Brooks, K.R., Zajkowski, M.E., Kriesler, A.D., Adams, C.E., Leonard, S., and Stevens, K.E (2014). Dietary choline supplementation to dams during pregnancy and lactation mitigates the effects of in utero stress exposure on adult anxiety-related behaviors. Behavioural Brain Research.

Pearson, J.N., Schulz, K.M., and Patel, M. (2014). Specific alterations in the performance of learning and memory tasks in models of chemoconvulsant-induced status epilepticus. Epilepsy Research.

Schulz K.M., Andrud K.M., Burke M.B., Pearson J.N., Kreisler A.D., Stevens K.E., Leonard S., and Adams C.E. (2013). The effects of prenatal stress on alpha4 beta2 and alpha7 hippocampal nicotinic acetylcholine receptor levels in adult offspring. Dev Neurobiol. 73(11):806-14.

Wu, P.H. and Schulz, K.M. (2012).Contributions of animal models to clinical treatment of addiction. ILAR J. 53(1):4-13

Delorme, K.C., Schulz, K.M., Salas-Ramirez, K.Y., and Sisk, C.L. (2012). Pubertal testosterone organizes regional volume and neuronal number in the medial amygdala of adult male Syrian hamsters. Brain Res.1460:33-40

Adams, C.E., Yonchek, J.C., Schulz, K.M., Graw, S.L., Stitzel, J., Teschke, P.U., Collins, A.C., and Stevens, K.E. (2012). Decreased Chrna7 expression in mice is associated with decreases in hippocampal markers of inhibitory function: implications for neuropsychiatric diseases. Neuroscience. 5; 207:274-82.

Schulz, K.M., Pearson, J.N., Neeley, E.W., Berger, R., Leonard, S., Adams, C.E., and Stevens, K.E. (2011). Maternal stress during pregnancy causes sex-specific alterations in offspring memory performance, social interactions, indices of anxiety, and body mass.  Physiology and Behavior. 104(2):340-7.

Schulz, K.M., Molenda-Figuera, H.R., and Sisk, C.L (2009).  Back to the Future:  The Organizational-Activational Hypothesis Adapted to Puberty and Adolescence.  Horm and Behav. 55(5):597-604. 1. 

Schulz, K.M., Zehr, J.L., Salas-Ramirez, K.Y., and Sisk, C.L (2009).  The timing of exposure to testosterone before, during, or after adolescence determines behavioral responses to testosterone in adulthood.  Endocrinology 150(8):3690-8.

Ahmed E.I., Zehr J.L., Schulz, K.M., Lorenz, B.H., Doncarlos, L.L., and Sisk, C.L. (2008).   Pubertal hormones modulate the addition of new neurons to sexually dimorphic brain regions.  Nature Neuroscience. 11(9), 995-997.

Zehr, J.L., Nichols, L.R., Schulz, K.M., and Sisk, C.L. (2008).  Adolescent development of neuron structure in dentate gyrus granule cells of male Syrian hamsters.  Dev Neurobiol. 68(14):1517-26.  PMCID: PMC2676582

Sato, S.M., Schulz, K.M., Sisk, C.L., and Wood, R.I. (2008).  Adolescents and androgens, receptors and rewards, Horm and Behav. 53(5), 647–658.

Meek, L.R., Schulz, K.M., & Keith, C.A (2006).  Effects of prenatal stress on sexual partner preference in mice.  Physiol and Beh. 89(2):133-8

Schulz, K.M., Menard, T.A., Smith, D.A., Albers, H.E. and Sisk, C.L. (2006).  Testicular hormone exposure during adolescence organizes flank marking behavior and vasopressin receptor binding in the lateral septum.  Horm and Behav. 50(3): 477-483.

Schulz, K.M. and Sisk, C.L. (2006).  Pubertal hormones, the adolescent brain, and the maturation of social behaviors:  Lessons from the Syrian Hamster.  Mol Cell  Endocrinol. 254-255: 120-6.

Zehr, J.L., Todd, B.J., Schulz, K.M., McCarthy, M.M., & Sisk, C.L. (2006).  Dendritic pruning of the medial amygdala during pubertal development of the male Syrian hamster.  J.Neurobiol. 66, 578-590.

Schulz, K.M., Richardson, H.N., Zehr, J.L., Osetek, A.J., Menard, T.A. and Sisk, C.L. (2004). Gonadal hormones masculinize and defeminize reproductive behaviors during puberty in the male Syrian hamster.  Horm and Behav. 45(4): 242-249.

Schulz, K.M., Richardson, H.N., Romeo, R.D., Morris, J.A., Lookingland, K.J., and Sisk, C.L. (2003).  Medial preoptic area dopaminergic responses to female pheromones develop during puberty in the male Syrian hamster. Brain Res.  988(1-2): 139-145.

Romeo R.D., Schulz, K.M., Nelson A.L., Menard T.A. and Sisk C.L. (2003).  Testosterone, puberty and the pattern of male aggression in Syrian hamsters.  Dev Psychobiol.  43(2): 102-8.

Sisk, C.L., Schulz, K.M., and Zehr, J.L. (2003).  Puberty:  A finishing school for male sexual behavior. Ann. N.Y. Acad. Sci. 1007: 189-198.

Meek, L.R., Schrump, S.E., Smith, D.A., Schulz, K.M., Dittel, P.L., Merkle, C.J. (2001).  Female meadow voles housed in long and short daylengths respond to exogenous estrogen with similar mating latencies. Physiol Behav 73:121-124.